Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Oxothiazolidinecarboxylic acid (Procysteine) 是半胱氨酸的前药,是一种抗氧化剂,它是惰性的,在细胞内代谢成半胱氨酸,从而刺激谷胱甘肽的合成。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
500 mg | ¥ 289 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 195 | 现货 |
产品描述 | Oxothiazolidinecarboxylic acid (Procysteine) is a precursor to glutathione (GSH) which is an important antioxidant in plants, animals, and fungi. |
体内活性 | Procysteine stimulated gene expression of anabolic factors such as insulin-like growth factor-1, ciliary neurotrophic factor, and cardiotrophin-1[2]. Procysteine supplementation eliminated the aging-associated differences in hepatic GSH and GSH/GSSG ratio. The nSMase activity and ceramide increased in the procysteine-fed mice irrespective of their age. The procysteine-fed aged mice also exhibited hepatic steatosis and triacylglyceride accumulation [3]. |
别名 | Oxothiazolidine carboxylate, Procysteine, 丙半胱氨酸 |
分子量 | 147.15 |
分子式 | C4H5NO3S |
CAS No. | 19771-63-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (373.77 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 6.7958 mL | 33.9789 mL | 67.9579 mL | 169.8947 mL |
5 mM | 1.3592 mL | 6.7958 mL | 13.5916 mL | 33.9789 mL | |
10 mM | 0.6796 mL | 3.3979 mL | 6.7958 mL | 16.9895 mL | |
20 mM | 0.3398 mL | 1.6989 mL | 3.3979 mL | 8.4947 mL | |
50 mM | 0.1359 mL | 0.6796 mL | 1.3592 mL | 3.3979 mL | |
100 mM | 0.068 mL | 0.3398 mL | 0.6796 mL | 1.6989 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Oxothiazolidinecarboxylic acid 19771-63-2 oxidation-reduction Antioxidant Oxothiazolidine carboxylate Procysteine inhibit 丙半胱氨酸 Inhibitor inhibitor